Molecular characterization of herpes simplex virus type 2 ( HSV - 2 ) strains 1 by analysis of microsatellite polymorphism 2 3 HSV - 2
نویسندگان
چکیده
4 Virology Department, Paul Brousse University Hospital, AP-HP, F-94804, Villejuif, France 12 13 14 15 Corresponding author: 16 Dr Sonia BURREL 17 Service de Virologie, Groupe Hospitalier Pitié-Salpêtrière, 83 boulevard de l'hôpital, F18 75651 Paris Cedex 13, France 19 Phone: +33 1 42 17 74 02 20 Fax: + 33 1 42 17 74 11 21 E-mail address: [email protected] 22 Manuscript word count: 3269 23 24 JCM Accepts, published online ahead of print on 21 August 2013 J. Clin. Microbiol. doi:10.1128/JCM.01714-13 Copyright © 2013, American Society for Microbiology. All Rights Reserved.
منابع مشابه
Molecular characterization of herpes simplex virus 2 strains by analysis of microsatellite polymorphism.
The complete 154-kbp linear double-stranded genomic DNA sequence of herpes simplex virus 2 (HSV-2), consisting of two extended regions of unique sequences bounded by a pair of inverted repeat elements, was published in 1998 and since then has been widely employed in a wide range of studies. Throughout the HSV-2 genome are scattered 150 microsatellites (also referred to as short tandem repeats) ...
متن کاملComparative Molecular PCR-RFLP Study of Native Herpes Simplex Virus Type 1 (HSV-1) with KOS Strain
Background: Recent research on several DNA fragments covering open reading frames (ORF) 1-37 shows a new genetic marker in ORF 6 which is specific for differentiating wild-type varicella-zoster virus (VZV) strains from Oka varicella vaccine strain. On the other hand, herpes simplex virus (HSV) genome analysis by restriction enzymes is used to differentiate types one and two of the virus and eve...
متن کاملThe Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes
Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection i...
متن کاملBackground: The thymidine kinase (TK) and DNA polymer- ase (pol) genes of herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are important targets for genotypic determination of HSV resistance to antiviral drugs
Background: The thymidine kinase (TK) and DNA polymerase (pol) genes of herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are important targets for genotypic determination of HSV resistance to antiviral drugs. The knowledge of gene polymorphism is an absolute requirement for the correct interpretation of genotypic findings. Methods: In this study, the natural polymorphism of TK and DNA pol...
متن کاملA Preliminary Study on the Molecular Identification of Herpes Simplex Virus Type 1 in Iranian Population
Herpes Simplex Virus Type 1 (HSV-1) is a member of the Herpesviridae family that causes herpetic disease in human. During the last 25-30 years, many investigations have been conducted on pathogenesis and molecular biology of this virus in several countries. In Iran HSV-1 has been isolated from patients and detected using immunological techniques. In this study, we investigated the molecular asp...
متن کامل